Assoc.Prof. Dr. Krassimira Idakieva
address: G. Bonchev, bl. 9, fl. 2, room 216
E-mail: idakieva@orgchm.bas.bg
Phone: + 359 2 960 6 190
Work experience
2005 - now
Institute of Organic Chemistry with a Centre of Phytochemistry
Assoc. prof.
1996 - 2005
Institute of Organic Chemistry with a Centre of Phytochemistry
Research fellow
Key words
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Protein chemistry
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Enzymes
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Hemocyanins
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Conformational stability of proteins
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Protein thermal stability
Expert activities
Education
1989
Bulgarian Academy of Sciences
Bioorganic Chemistry
PhD
1980
University of Chemical Technology and Metallurgy - Sofia
Engineering Chemistry
Master
2010 - present
Significant publications
1. Raynova, Y., Doumanova, L., Idakieva, K. Phenoloxidase activity of Helix aspersa maxima (garden snail, Gastropod) hemocyanin. (2013) Protein J., 32, 609-618.
2. Idakieva, K., Raynova, Y., Meersman, F., Gielens, C. Phenoloxidase activity and thermostability of Cancer pagurus and Limulus polyphemus hemocyanin. (2013) Comp. Biochem. Physiol. B, 164, 201-209.
3. Idakieva, K., Meersman, F., Gielens, C. Reversible heat inactivation of copper sites precedes thermal unfolding of molluscan (Rapana thomasiana) hemocyanin. (2012) Biochim. Biophys. Acta, 1824, 731-738.
4. Idakieva, K., Parvanova, K., Todinova, S. (2005) Differential scanning calorimetry of the irreversible denaturation of Rapana thomasiana (marine snail, Gastropod) hemocyanin, Biochim. Biophys. Acta, 1748, 50-56.
5. Perbandt, M., Guthöhrlein, E., Rypniewski, W., Idakieva, K., Stoeva, S., Voelter, W., Genov, N., Betzel, Ch. (2003) The structure of a functional unit from the wall of a Gastropod hemocyanin offers a possible mechanism for cooperativity, Biochemistry 42, 6341-6346.
2010 - present
Significant projects
1. Antitumor activity of gastropodan hemocyanins, project number: DTK 02/78,project leader: Assoc.prof. Dr K. Idakieva, duration: 2010-2014;
Funding: National Science Fund of Bulgaria
2. Development of biotechnology for obtaining biologically active substances from the Rapana thomasiana hemocyanin, project number: ТК-Х-1611, project leader: Assoc.prof. Dr K. Idakieva, duration 2006-2010;
Funding: National Science Fund of Bulgaria